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Real American Society of Microbiology ABMM practice exam questions for easy pass!
Updated: Sep 04, 2025
No. of Questions: 204 Questions & Answers with Testing Engine
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American Society of Microbiology ABMM Sample Questions:
1. A clinical microbiology laboratory is investigating a potential outbreak of a highly contagious respiratory virus. To rapidly screen a large number of nasopharyngeal swabs, the MOST appropriate initial diagnostic test would be:
A) Viral culture on a broad range of cell lines.
B) Electron microscopy of the samples.
C) Rapid antigen detection assay.
D) Whole-genome sequencing of viral RNA.
2. A research laboratory is investigating the mechanisms of antigenic variation in Trypanosoma brucei, the causative agent of African trypanosomiasis. The parasite evades the host immune response by periodically changing its surface coat protein. This process primarily involves:
A) RNA interference-mediated silencing of expressed VSG genes followed by activation of a new VSG gene.
B) Recombination between different VSG gene loci on minichromosomes.
C) Segmental gene conversion events involving a large repertoire of silent VSG genes.
D) High-frequency point mutations in the gene encoding the variant surface glycoprotein (VSG).
3. A research laboratory is developing a novel diagnostic assay for early detection of sepsis. They are investigating the use of host biomarkers that are rapidly upregulated in response to bacterial infection. Which of the following biomarkers has shown promise for differentiating between systemic inflammatory response syndrome (SIRS) and sepsis?
A) Interleukin-6 (IL-6)
B) Erythrocyte sedimentation rate (ESR)
C) Procalcitonin (PCT)
D) C-reactive protein (CRP)
4. A patient with HIV infection and a very low CD4+ T-cell count develops a disseminated infection with a fungus that is commonly found in pigeon droppings. The MOST likely causative agent is:
A) Cryptococcus gattii
B) Cryptococcus neoformans
C) Candida glabrata
D) Saccharomyces cerevisiae
5. A patient with a history of neutropenia following chemotherapy develops a severe pneumonia.
Bronchoalveolar lavage fluid reveals the presence of hyaline, septate hyphae with frequent dichotomous branching at acute angles. Culture yields a filamentous fungus that produces conidiophores with a vesicle bearing phialides that release chains of conidia. The MOST likely genus is:
A) Aspergillus
B) Fusarium
C) Rhizopus
D) Mucor
Solutions:
| Question # 1 Answer: C | Question # 2 Answer: C | Question # 3 Answer: C | Question # 4 Answer: B | Question # 5 Answer: A |
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