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Real ASCP ASCP-MLT practice exam questions for easy pass!

Last Updated: Aug 06, 2026

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ASCP ASCP-MLT Exam Syllabus Topics:

SectionWeightObjectives
Topic 1: Microbiology15–20%- Bacteriology and mycology procedures
- Virology and parasitology testing
Topic 2: Chemistry20–25%- Electrolytes, acid-base, and toxicology
- Carbohydrates, lipids, and enzymes
Topic 3: Blood Banking15–20%- Blood products and components
- Blood group systems and immunology
- Transfusion practice and testing
Topic 4: Hematology20–25%- Laboratory testing and hemostasis
- Physiology and disease states
Topic 5: Immunology5–10%- Principles of immunology
- Serologic procedures and immune diseases
Topic 6: Urinalysis and Other Body Fluids5–10%- Physical and chemical testing
- Microscopic analysis and disease correlation
Topic 7: Laboratory Operations5–10%- Quality assessment and safety
- Instrumentation and laboratory mathematics

ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. Skeletal deformations result from the increased erythropoiesis that occurs in beta thalassemia major. Children with beta thalassemia intermedia may demonstrate some facial bone deformity, however this is not common.
Beta thalassemia minor rarely causes any physical signs or symptoms and beta thalassemia minima is completely asymptomatic.
Skeletal deformations are most commonly present in which of the following beta thalassemias?

A) Beta thalassemia major
B) None of the beta thalassemias
C) All of the beta thalassemias equally
D) Beta thalassemia minor
E) Beta thalassemia intermedia


2. The most common specimen analyzed in the hematology section is:

A) serum.
B) urine.
C) plasma.
D) whole blood.


3. One agency that accredits education programs for clinical laboratory personnel is the:

A) North Central Association (NCA)
B) American Society for Clinical Laboratory Science (ASCLS)
C) National Accrediting Agency for Clinical Laboratory Sciences (NAACLS)
D) American Society for Clinical Pathology (ASCP)


4. What additional fraction would be seen if plasma rather than serum was subjected to electrophoresis:

A) Fibrinogen
B) Alpha-2 macroglobulin
C) Gamma globulins
D) Alpha-1 antitrypsin


5. The conidia of Exophiala species are produced within phialides that extrude the conidia in tight, ball-like clusters.
The large, drum stick-shaped muriform macroconidia of Alternaria species are arranged in short chains; the small, elliptical conidia of Cladosporium species are arranged in both long and short, branching chains.
Which of the following dematiaceous fungal species produce conidia in clusters?

A) Exophiala species
B) Alternaria species
C) Cladosporium species


Solutions:

Question # 1
Answer: A
Question # 2
Answer: D
Question # 3
Answer: C
Question # 4
Answer: C
Question # 5
Answer: A

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